Skip to content

: MR-Guided Bone Cryoablation

Published: August 9, 2026Updated: August 16, 2026

: MR-guided bone cryoablation is a minimally invasive image-guided procedure that uses magnetic resonance imaging (MRI) to guide the freezing of selected bone tumors or painful bone lesions. It is typically performed by an interventional radiology team and is intended to destroy targeted tissue while sparing surrounding structures.

Quick summary

[": This is an image-guided ablation procedure, not a laboratory blood test, that uses MRI guidance and extreme cold to treat selected bone lesions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
100881-2
Short code
MR Guided Bone Cryoablation
Synonyms
MR Guided Bone Cryoablation
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What This Procedure Is

: Cryoablation means using very cold temperatures to freeze and destroy abnormal tissue. In this version, magnetic resonance imaging (MRI) is used to show the target and to help guide the treatment probe into a bone lesion, with images used during the procedure to monitor the freezing area.

: Why It May Be Used

: Clinicians may consider MR-guided bone cryoablation for selected benign or cancerous bone tumors, particularly when surgery is not preferred or when the goal is to relieve pain from a bone lesion. Suitability depends on the lesion's location, size, and relationship to nerves, blood vessels, and other important structures.

: How the Procedure Is Performed

: The procedure is usually done under local anesthesia with sedation or general anesthesia, depending on the case. A thin probe is placed into the lesion under imaging guidance, and controlled cooling is applied through the probe. MRI is used to help confirm probe position and to watch the treated area during freezing.

: What to Expect and Possible Risks

: After the procedure, you may have soreness at the treatment site and will typically be observed for a period of time. As with any invasive procedure, possible risks include bleeding, infection, injury to nearby nerves or tissues, skin or bone injury from the cold, and incomplete treatment. Your care team will explain expected recovery and warning signs to watch for.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

: MR-guided bone cryoablation is a specialized interventional oncology or musculoskeletal procedure, not a laboratory assay, so there are no serum or urine reference ranges associated with it. Its clinical value involves local tumor control or symptom relief in carefully selected patients, and decisions about whether it is appropriate require review of imaging and other clinical information by the treating team.

Short name

: NONE

Frequently asked questions

: Is MR-guided bone cryoablation a blood test?
: No. It is an image-guided treatment procedure that uses MRI and extreme cold to destroy selected bone lesions; it is not a laboratory test ordered on blood, urine, or other body fluids.
: How is the target area monitored during the procedure?
: The interventional team uses MRI guidance to place the treatment probe and to monitor the treated area while the cold is applied. This helps the team assess coverage of the lesion and avoid injury to nearby important structures.
: Can I decide on this treatment without a specialist evaluation?
: No. Whether this procedure is suitable depends on the specific lesion, your symptoms, your overall health, and imaging findings. An interventional radiology or cancer care specialist should review your case and discuss alternatives, benefits, and risks with you.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy