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Serum/plasma mass concentration of guided breast lesion localization element (e.g., contrast agent uptake or tracer for imaging-guided biopsy)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of a specialized substance used in certain diagnostic procedures to help locate and guide biopsies or other targeted interventions in breast tissue.

Quick summary

["This test is typically used during specialized medical imaging to assist in precise tissue sampling."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107387-3
Short code
MR Guided Brst-L localize lesion
Synonyms
MR Guided Brst-L localize lesion
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is This Test Used For?

This test is part of a procedure called **guided breast lesion localization**, often used when a mammogram or ultrasound identifies a suspicious area that may require a biopsy. The test involves injecting a specific substance (e.g., a contrast agent) that helps pinpoint the exact location of the lesion for accurate sampling. This ensures that the biopsy targets the correct area, improving diagnostic accuracy.

How Is the Sample Collected?

A blood sample (serum or plasma) is drawn from a vein in your arm. This sample is then analyzed to measure the concentration of the substance used during the imaging procedure. The timing of the blood draw may depend on when the contrast agent was administered during the imaging process.

What Does the Result Mean?

The result provides quantitative data on the presence and concentration of the localization element in your bloodstream. This information helps healthcare providers confirm the correct placement of the needle or other instruments during the biopsy procedure. Abnormal or unexpected levels may indicate issues with the procedure’s accuracy or potential complications.

When Might This Test Be Needed?

This test is almost always performed as part of a **guided biopsy procedure** when a breast lesion is suspected but not clearly defined by imaging alone. It is not a standalone diagnostic test but rather a tool to assist in precise tissue sampling for further evaluation, such as a biopsy or surgical excision.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for ensuring that biopsies are performed accurately, reducing the risk of missing the lesion or sampling incorrect tissue. Accurate localization improves diagnostic reliability and helps guide treatment decisions, particularly in cases where breast cancer or other abnormalities are suspected. The results help confirm that the biopsy was successful and that the sampled tissue is representative of the lesion identified on imaging.

Frequently asked questions

Why would my doctor order this test?
Your doctor may order this test if they suspect a breast lesion that cannot be precisely localized using imaging alone, such as a mammogram or ultrasound. It helps ensure that a biopsy is performed accurately, which is essential for diagnosing conditions like breast cancer or other abnormalities.
What does a high or low level of this substance mean?
A high level of the localization element typically indicates successful administration and uptake during the imaging procedure, confirming the needle or instrument was placed correctly. A low or unexpected level may suggest issues with the procedure, such as incorrect needle placement or incomplete administration of the substance.
Is this test painful or uncomfortable?
The blood draw itself may cause mild discomfort, but the procedure is quick and usually not painful. The discomfort from the guided biopsy procedure (where this test is used) depends on the technique and location but is generally managed with local anesthesia.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy