MRI-Guided Biopsy of the Pleura
This is a procedure in which magnetic resonance imaging (MRI) is used to guide a needle into the pleura—the thin lining around the lungs—to collect a tissue sample for laboratory examination.
["An MRI-guided pleural biopsy helps doctors obtain a tissue sample from the lung lining while using MRI to target the area and guide the needle."]
Key facts at a glance
- LOINC
- 69200-4
- Short code
- MR Guided Chest Pleura Bx
- Synonyms
- MR Guided Chest Pleura Bx
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- mr
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What the Test Is
The pleura is the membrane that surrounds the lungs and lines the chest cavity. In an MRI-guided pleural biopsy, a doctor uses magnetic resonance imaging to locate an abnormal area of the pleura and then guides a biopsy needle to that spot to collect a small piece of tissue. The tissue is then sent to a laboratory for examination by a pathologist.
Why It May Be Done
This procedure may be recommended when imaging or other tests show thickening, fluid, or an abnormal growth involving the pleura, and a tissue sample is needed to find the cause. Examining pleural tissue can help evaluate conditions such as infection, inflammation, or cancer involving the lining of the lungs.
How It Is Performed
MRI uses a strong magnet and radio waves rather than X-rays to create detailed images, so it does not involve radiation exposure. You may be given a contrast agent and local numbing medicine or sedation depending on the plan your care team chooses. The radiologist uses the MRI images to guide the needle to the target area and withdraw a small tissue sample.
After the Procedure
After the sample is collected, you may be monitored for a short time for bleeding, pain, or other effects. The tissue is processed and examined in the laboratory, and results are usually discussed with you by your healthcare team at a follow-up visit.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
An MRI-guided pleural biopsy can provide important tissue information when pleural abnormalities need to be explained, helping distinguish among infectious, inflammatory, and malignant causes. Because it uses magnetic fields and radio waves, it avoids ionizing radiation, though the specific risks and benefits depend on your individual situation and should be discussed with your care team.
Short name
MRI-Guided Pleural Biopsy
Frequently asked questions
Will the biopsy hurt?
How long does it take to get results?
Is MRI-guided biopsy safe?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy