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MRI-Guided Biopsy of the Pleura

Published: August 9, 2026Updated: August 16, 2026

This is a procedure in which magnetic resonance imaging (MRI) is used to guide a needle into the pleura—the thin lining around the lungs—to collect a tissue sample for laboratory examination.

Quick summary

["An MRI-guided pleural biopsy helps doctors obtain a tissue sample from the lung lining while using MRI to target the area and guide the needle."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
69200-4
Short code
MR Guided Chest Pleura Bx
Synonyms
MR Guided Chest Pleura Bx
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What the Test Is

The pleura is the membrane that surrounds the lungs and lines the chest cavity. In an MRI-guided pleural biopsy, a doctor uses magnetic resonance imaging to locate an abnormal area of the pleura and then guides a biopsy needle to that spot to collect a small piece of tissue. The tissue is then sent to a laboratory for examination by a pathologist.

Why It May Be Done

This procedure may be recommended when imaging or other tests show thickening, fluid, or an abnormal growth involving the pleura, and a tissue sample is needed to find the cause. Examining pleural tissue can help evaluate conditions such as infection, inflammation, or cancer involving the lining of the lungs.

How It Is Performed

MRI uses a strong magnet and radio waves rather than X-rays to create detailed images, so it does not involve radiation exposure. You may be given a contrast agent and local numbing medicine or sedation depending on the plan your care team chooses. The radiologist uses the MRI images to guide the needle to the target area and withdraw a small tissue sample.

After the Procedure

After the sample is collected, you may be monitored for a short time for bleeding, pain, or other effects. The tissue is processed and examined in the laboratory, and results are usually discussed with you by your healthcare team at a follow-up visit.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An MRI-guided pleural biopsy can provide important tissue information when pleural abnormalities need to be explained, helping distinguish among infectious, inflammatory, and malignant causes. Because it uses magnetic fields and radio waves, it avoids ionizing radiation, though the specific risks and benefits depend on your individual situation and should be discussed with your care team.

Short name

MRI-Guided Pleural Biopsy

Frequently asked questions

Will the biopsy hurt?
You may receive local numbing medicine or sedation to reduce discomfort. Some pressure or soreness at the biopsy site is common afterward, and your care team can advise on managing it.
How long does it take to get results?
Tissue samples usually require processing and examination by a pathologist, so results are typically not available immediately. Your healthcare team will tell you when to expect them.
Is MRI-guided biopsy safe?
MRI-guided biopsy is generally considered a safe procedure, but like any needle biopsy it carries small risks such as bleeding or infection. Your care team will review your individual risks and answer questions before the procedure.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy