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Serum or Plasma Creatinine Concentration (Standard Method)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle breakdown, in your blood or urine. It helps assess how well your kidneys are filtering blood.

Quick summary

["A creatinine test helps check kidney function by measuring how well your kidneys remove waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
24880-7
Short code
MR Pit+Sella turc
Synonyms
MR Pit+Sella turc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine levels can indicate how well your kidneys are working. High levels may suggest kidney problems, while low levels could indicate dehydration or muscle loss. This test is often used alongside other kidney function tests to diagnose and monitor conditions like chronic kidney disease.

What to Expect Before the Test

You may be asked to fast for a few hours before the test, but this depends on the type of test (blood or urine). For a blood test, a small sample is taken from a vein in your arm. For a urine test, you may collect a sample at home or in the lab. Drink plenty of water if instructed, as it can help prepare your body for the test.

Common Causes of Abnormal Results

High creatinine levels might be due to kidney disease, dehydration, or conditions that reduce blood flow to the kidneys. Low levels can result from dehydration, muscle breakdown, or certain medical conditions. Always discuss your results with your healthcare provider.

How Results Are Interpreted

Your healthcare provider will compare your results with standard ranges and consider your overall health. They may also review other tests or medical history to provide a full picture. Never interpret results on your own.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Creatinine levels are a key indicator of kidney function. Elevated levels often signal impaired kidney function, which can lead to complications like fluid buildup, electrolyte imbalances, or even heart problems. Regular monitoring is important for people with chronic kidney disease or risk factors like diabetes or high blood pressure.

Short name

Creatinine

Frequently asked questions

What does a creatinine test tell me about my kidneys?
A creatinine test helps assess how well your kidneys are filtering waste from your blood. High levels may suggest kidney problems, while low levels could indicate dehydration or muscle issues. It’s part of a broader evaluation for kidney function.
Do I need to prepare for this test?
Preparation depends on the test type. For blood tests, you may need to fast briefly. For urine tests, follow your provider’s instructions, often involving collecting a sample at home or in the lab. Drink water as directed to help prepare your body.
Can diet affect my creatinine levels?
Diet can influence creatinine levels indirectly. High-protein diets may temporarily increase muscle breakdown, raising creatinine. Avoiding excessive protein or dehydration can help stabilize results. Always discuss dietary changes with your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy