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Total Bilirubin (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of bilirubin in your blood. Bilirubin is a yellow pigment produced when red blood cells break down, and it helps the liver process waste products.

Quick summary

["Bilirubin helps identify liver function and bile flow issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
77101-4
Short code
MRPL18A Fam Mut Anl Bld/T
Synonyms
MRPL18A Fam Mut Anl Bld/T
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order a total bilirubin test to check for liver disease, such as hepatitis, cirrhosis, or bile duct blockages. It can also help diagnose conditions like gallstones or certain blood disorders. Sometimes, it’s used to monitor treatment progress for conditions affecting the liver or bile system.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood. If you’re nervous, let your healthcare provider know—they can help make it more comfortable.

What Happens During the Test

A healthcare professional will clean the area on your arm, insert a needle, and collect a small amount of blood. The process usually takes a few minutes. You may feel a slight pinch, but it’s over quickly.

What the Results Mean

Your results will show the total bilirubin level in your blood. High levels may suggest liver problems, while low levels are usually normal. Your doctor will interpret the results in the context of your overall health and symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated bilirubin levels can indicate conditions like jaundice (yellowing of the skin and eyes), liver disease, gallbladder issues, or hemolytic anemia (destruction of red blood cells). Low levels are typically normal but may be checked if you have certain medical conditions. Your doctor will discuss findings with you based on your symptoms and medical history.

Short name

Total Bilirubin

Frequently asked questions

What causes bilirubin levels to be high?
High bilirubin levels can result from liver problems (like hepatitis or cirrhosis), blockages in the bile ducts, or increased breakdown of red blood cells. Jaundice, a condition causing yellowing of the skin and eyes, is a common sign of elevated bilirubin.
How long does it take to get results?
Results are usually available within a few days, depending on your lab’s processing time. Your doctor will contact you once they have the results to discuss them further.
Can I eat or drink before this test?
No special diet is required before this test. You can eat and drink normally unless your doctor has instructed otherwise.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy