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Serum Calcium Concentration (Total)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of calcium in your blood serum. Calcium is an essential mineral for many bodily functions, including bone health, muscle and nerve function, and blood clotting.

Quick summary

["Your blood calcium levels help ensure proper bone strength and normal heart and nerve function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
36060-2
Short code
MR Sacrum+Coccyx
Synonyms
MR Sacrum+Coccyx
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why It’s Done

Doctors may order a total serum calcium test to check for conditions like low or high calcium levels, which can cause symptoms such as muscle cramps, weakness, or abnormal heart rhythms. It’s also used to monitor certain medical treatments or conditions, such as kidney disease, bone disorders, or hyperparathyroidism.

What to Expect

A blood sample is taken from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The test is quick and typically done in a doctor’s office or lab. No special preparation is needed unless instructed otherwise.

Possible Results and Interpretation

Results are compared to standard reference ranges, but exact values can vary by lab. Low calcium levels (hypocalcemia) may indicate conditions like vitamin D deficiency or kidney problems, while high levels (hypercalcemia) could signal overactive thyroid, cancer, or other metabolic issues.

Common Conditions Affecting Results

Changes in calcium levels can be influenced by diet, medications (like calcium supplements or certain diuretics), thyroid disorders, or chronic illnesses. If you’re on long-term medication or have a known condition, your doctor may adjust test timing or frequency.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Serum Calcium

Frequently asked questions

How often will I need this test?
The frequency depends on your health status. If you have a chronic condition like kidney disease or osteoporosis, your doctor may recommend testing every few months or annually. Healthy individuals may only need it if symptoms appear or as part of routine check-ups.
What causes low or high calcium levels?
Low calcium can result from poor vitamin D absorption, kidney issues, or certain medications. High calcium may be linked to overactive thyroid, cancer, or prolonged immobilization. Lifestyle factors like diet (excessive dairy or calcium supplements) can also play a role.
Can diet affect my calcium test results?
Yes, diet can influence calcium levels. Consuming large amounts of calcium-rich foods or supplements shortly before testing may skew results. Your doctor may advise timing your meal or supplement intake around the test to get accurate readings.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy