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Staphylococcus aureus Methicillin Resistance Detection by mecA Gene Presence (PCR-based)

Published: August 9, 2026Updated: August 17, 2026

This test checks for the presence of the *mecA* gene, which helps determine if certain *Staphylococcus aureus* bacteria are resistant to common antibiotics like penicillin and methicillin.

Quick summary

["Helps identify antibiotic-resistant bacteria that may require different treatment plans."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
94424-9
Short code
MRSA SCCmec+orfX Islt/Spm Ql
Synonyms
MRSA SCCmec+orfX Islt/Spm Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0
Ref high
2
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
CPT
86430
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Antibiotic resistance, including MRSA, can make infections harder to treat. This test helps doctors choose the best antibiotics to fight infection safely and effectively.

How the Test Works

The test uses a small sample of blood or other bodily fluid to detect the *mecA* gene, which is linked to MRSA resistance. A special lab process (PCR) amplifies and identifies this genetic marker.

Sample Collection

You may have a blood draw or provide a swab sample (e.g., from a wound or nasal passage) depending on the clinical need. The lab processes the sample to check for the *mecA* gene.

What to Expect After the Test

Results are typically ready within a few days. If positive, it means the bacteria may be resistant to certain antibiotics, guiding your doctor’s treatment plan.

Reference range

NCBI: SCC <2.0 ng/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Understanding MRSA and Treatment

Short name

MRSA mecA Gene Screening

Frequently asked questions

MRSA is a type of *Staphylococcus aureus* bacteria that can cause infections in skin, wounds, or even bloodstream. Detecting the *mecA* gene helps doctors avoid using ineffective antibiotics, reducing the risk of antibiotic resistance spreading.
This test is often used in hospitals, clinics, or for patients with known or suspected infections. It helps prevent unnecessary antibiotic use and ensures targeted treatment.
What does a positive result mean?
A positive result indicates the presence of the *mecA* gene, suggesting the bacteria may be resistant to certain antibiotics like methicillin. Your doctor will discuss the next steps, such as alternative treatments or monitoring.
How long does it take to get results?
Results are usually available within 2–5 business days, depending on lab processing times. Your healthcare provider will contact you once results are ready.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy