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Mitochondrial Respiratory Testing — With Control

Published: August 9, 2026Updated: August 16, 2026

A laboratory test that evaluates mitochondrial respiratory function. A control sample is included to help verify that the test results are valid.

Quick summary

["The control helps confirm that the laboratory test worked correctly; your clinician will interpret the result in the context of your symptoms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
37286-2
Short code
MR TMJ-L WO contr
Synonyms
MR TMJ-L WO contr
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

Mitochondrial respiratory testing evaluates how efficiently mitochondria produce energy from nutrients. The abbreviated test name includes a control, which is used to check the performance and validity of the laboratory assay.

Why might I need this test?

This test may be used when symptoms suggest an impairment in cellular energy production, such as unusual muscle weakness, exercise intolerance, fatigue, or problems affecting more than one organ system. Testing may also be part of an evaluation for a suspected mitochondrial disorder.

How is the test performed?

A laboratory technician analyzes a patient sample according to the specific laboratory method and compares it with a control. The type of specimen and testing procedure depend on the exact ordered assay, so the laboratory or ordering clinician should provide those details.

How do I prepare for the test?

Follow the preparation instructions provided by the laboratory. Some mitochondrial tests require fasting, timed collection, or avoidance of strenuous exercise beforehand; do not stop prescribed medicines unless your clinician instructs you to do so.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Abnormal results may indicate reduced mitochondrial energy production and can occur with mitochondrial disorders or certain other conditions. An abnormal control, poor sample quality, medication effects, or another pre-analytical issue can also affect the result, so your clinician should interpret the complete laboratory report.

Short name

Mitochondrial respiratory test

Frequently asked questions

What does the control result mean?
The control shows whether the assay is performing as expected. It helps the laboratory determine whether the patient result can be trusted.
Does an abnormal result always mean I have a mitochondrial disorder?
No. Abnormal results can have several causes, including mitochondrial disorders, other illnesses, medications, or sample-handling issues. Interpretation requires the full report and your medical history.
What specimen is used for this test?
The specimen cannot be determined reliably from the abbreviated test name alone. It may involve blood, urine, tissue, or another sample, depending on the exact laboratory assay.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy