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Serum or plasma mass concentration of total bilirubin

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of bilirubin, a yellow pigment produced when your body breaks down old red blood cells. High levels may indicate liver disease, bile duct problems, or hemolysis.

Quick summary

["Bilirubin helps diagnose liver function and bile flow issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
37231-8
Short code
MR TMJ-R
Synonyms
MR TMJ-R
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
mr
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Bilirubin is a waste product from red blood cell breakdown. Normally, it’s filtered by your liver and excreted in bile. If your body produces too much bilirubin or your liver can’t process it, levels rise in your blood or urine. This can signal problems like jaundice, liver disease, or blockages in the bile ducts.

When You Might Need It

Your doctor may order this test if you have symptoms like jaundice (yellowing of skin/eyes), unexplained fatigue, dark urine, pale stools, or if they suspect liver disease, gallbladder issues, or hemolytic anemia.

Common Causes of Abnormal Results

High bilirubin can stem from liver conditions (e.g., hepatitis), bile duct obstructions, or red blood cell disorders. Low levels are less common but may occur with certain medications or liver damage.

What to Expect During the Test

A simple blood draw is used. You’ll lie down while a healthcare provider inserts a needle into your arm. The blood is sent to a lab for analysis. No special preparation is needed, but fasting may be advised for some related tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Bilirubin Level

Frequently asked questions

What does my bilirubin level mean?
Your results will be compared to standard ranges for your age/gender. High levels may prompt further testing for liver function or bile flow issues. Low levels may need investigation for underlying causes like medications or liver disease.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Your doctor will discuss them with you during your follow-up visit.
Can I eat or drink before this test?
No special diet is required for this test alone, but check with your doctor if you’re also having fasting tests (e.g., liver function panels). Avoid alcohol or certain medications that may affect liver function.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy