Mycobacterium tuberculosis complex RNA, qualitative nucleic acid amplification test (specimen: respiratory sample)
This test checks for genetic material from *Mycobacterium tuberculosis* (TB bacteria) in a sample from your respiratory tract, such as sputum or induced sputum. It helps determine if you may have active TB infection.
["A quick way to screen for TB bacteria in your lungs or airways."]
Key facts at a glance
- LOINC
- 48174-7
- Short code
- M TB Cmplx rRNA Spec Ql NAA+probe
- Synonyms
- M TB Cmplx rRNA Spec Ql NAA+probe
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
How the Test Works
The test uses a specialized probe to detect RNA from TB bacteria. If TB bacteria are present, their genetic material will react with the probe, triggering a positive result. This method is highly sensitive and can detect TB even when traditional tests may not.
What to Expect Before the Test
No special preparation is needed. You may be asked to provide a sample of sputum (phlegm) after coughing deeply into a container, or you might have a procedure to induce sputum production if needed. If you have a respiratory condition, your healthcare provider may guide you on how to prepare.
What to Expect During the Test
The test is typically done in a lab setting. You’ll provide a sample (like sputum), which is then processed and analyzed using a molecular technique. Results are usually available within a few days.
Possible Results and Next Steps
A positive result means the test detected TB RNA, suggesting you may have an active TB infection. A negative result means no TB RNA was found in the sample. Follow-up testing or further evaluation by a healthcare provider may be needed based on your symptoms and clinical picture.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
TB RNA Test (Screen)
Frequently asked questions
What does a positive result mean?
Can I get TB from this test?
How accurate is this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy