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Prostate-Specific Antigen (PSA) in Serum by Immunoassay (Qualitative Probe)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of prostate-specific antigen (PSA), a protein produced by the prostate gland, using a qualitative probe method. It helps assess potential prostate health concerns.

Quick summary

["PSA qualitative testing helps detect early signs of prostate issues, including cancer or inflammation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
78357-1
Short code
M tb DNA BAL Ql NAA+probe
Synonyms
M tb DNA BAL Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

PSA (prostate-specific antigen) is a protein made mostly by healthy prostate cells. While it’s found in small amounts in other tissues, high levels can signal possible prostate problems, such as inflammation, infection, or cancer. This test detects PSA using a specialized probe to determine its presence in your blood.

How the Test Works

Your blood sample is analyzed using a sensitive immunoassay (a lab test that detects specific proteins) with a probe to identify PSA. The result is reported as either positive (PSA present) or negative (PSA not detected), rather than a numerical value.

Why It’s Done

A qualitative PSA test may be used as part of a screening or diagnostic process, particularly when further evaluation is needed for symptoms like urinary changes, pain, or concerns about prostate health. It’s not typically used alone for routine check-ups.

Common Reasons for Testing

This test might be ordered if you have symptoms like difficulty urinating, pain in the pelvic area, or if you’re at higher risk for prostate issues due to age, family history, or other medical conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

PSA Qualitative Probe

Frequently asked questions

What Does a Positive Result Mean?
A positive result means PSA was detected in your blood sample. This doesn’t confirm a diagnosis of prostate cancer but may prompt additional testing to explore underlying causes, such as inflammation or other conditions.
How Often Should I Get This Test?
The frequency depends on your health history and doctor’s recommendations. Routine PSA screening isn’t recommended for all men, but your healthcare provider will decide based on your individual needs and risk factors.
Can Diet or Medications Affect This Test?
Certain medications (like finasteride or dutasteride) or conditions (such as prostate infection or recent ejaculation) can influence PSA levels. Your doctor may advise avoiding these factors before testing to get the most accurate result.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy