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Bronchial Lavage Fluid Alpha-1 Antitrypsin (A1AT) Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of alpha-1 antitrypsin, a protein that helps protect your lungs from damage caused by enzymes released during inflammation. It may be used to assess lung health or inflammation in conditions like chronic obstructive pulmonary disease (COPD).

Quick summary

["This test helps evaluate lung function and inflammation by checking for abnormal levels of alpha-1 antitrypsin in lung fluid."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14557-3
Short code
M tb DNA Bronch Ql NAA+probe
Synonyms
M tb DNA Bronch Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like persistent cough, shortness of breath, or lung-related conditions such as COPD, cystic fibrosis, or other inflammatory lung diseases. It can also be used to monitor lung function in certain genetic disorders or after lung injury.

What to Expect Before the Test

Bronchial lavage involves inserting a thin tube through your nose or mouth into your airways to collect fluid from your lungs. You may experience mild discomfort, but it is generally well-tolerated. Follow any specific instructions your provider gives you, such as avoiding certain medications or foods before the procedure.

What the Test Results Mean

Abnormally low levels of alpha-1 antitrypsin in lung fluid may indicate lung damage or inflammation. High levels could be related to certain genetic conditions or other underlying health issues. Your healthcare provider will discuss the results in the context of your overall health and symptoms.

Common Conditions Monitored or Diagnosed

This test can help diagnose or monitor conditions like alpha-1 antitrypsin deficiency, which can lead to lung diseases such as emphysema. It may also be used to assess lung inflammation in other respiratory conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

A1AT in Bronchial Lavage Fluid

Frequently asked questions

What does a low level of alpha-1 antitrypsin in lung fluid mean?
A low level may suggest lung inflammation or damage, which could be linked to conditions like chronic lung diseases or genetic disorders affecting protein production. Your doctor will review these results alongside your medical history and other tests to determine the next steps.
How often will I need this test?
The frequency depends on your health condition and treatment plan. If you have a known lung disorder or genetic predisposition, your provider may recommend regular monitoring to track changes in your lung function and protein levels.
Can I eat or drink anything before this test?
Typically, you may need to fast or follow specific dietary instructions, but always confirm with your healthcare provider. Avoid smoking or using tobacco products before the procedure as they can affect lung fluid composition.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy