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C-reactive protein (CRP) with probe-based immunoassay measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein in your blood that rises when your body is fighting inflammation, often used to check for low-grade inflammation or infection.

Quick summary

["High CRP levels may signal inflammation, which can be linked to conditions like autoimmune diseases or infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88165-6
Short code
M tb DNA Corn/Cnjt Ql NAA+probe
Synonyms
M tb DNA Corn/Cnjt Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why It’s Ordered

Your healthcare provider may order this test to monitor chronic conditions like rheumatoid arthritis, lupus, or heart disease, or to check for signs of infection, especially if symptoms aren’t obvious. It can also help assess response to treatments for inflammation.

What to Expect Before the Test

No special preparation is needed. You may have blood drawn from a vein in your arm. If you’re on blood thinners, let your provider know before the test.

What the Results Mean

Results are typically reported in milligrams per liter (mg/L). Higher than normal levels may indicate inflammation, while very low levels might suggest a lack of inflammation. Your provider will interpret results in the context of your health history.

Common Conditions Monitored

This test is often used to track inflammation in conditions like cardiovascular disease, inflammatory bowel disease, or after surgery to check for healing responses.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: CRP is a marker for systemic inflammation. Elevated levels can signal acute infections, chronic diseases (e.g., arthritis), or responses to immune challenges. It’s less specific than some tests but useful for broad monitoring.

Short name

CRP (High-Sensitivity)

Frequently asked questions

What causes CRP levels to change?
CRP levels can rise due to infections (bacterial or viral), injuries, surgeries, or certain medications. They may also be lower in people with suppressed immune activity or certain genetic conditions.
How often should I get this test?
Frequency depends on your condition. For example, people with heart disease may get it every few months, while others with stable chronic conditions might have it less often. Always follow your provider’s advice.
Can diet or exercise affect CRP levels?
Yes! Reducing inflammation through diet (e.g., Mediterranean diet), exercise, and managing stress can lower CRP levels. Avoiding smoking and managing weight also play a role.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy