Molecular Test for Detection of Mycobacterium tuberculosis DNA in Sputum
This test checks for genetic material from *Mycobacterium tuberculosis*, the bacteria responsible for tuberculosis (TB). It helps determine if you have an active TB infection by detecting its DNA in your sputum.
["A TB DNA test can help confirm or rule out TB infection faster than traditional cultures."]
Key facts at a glance
- LOINC
- 107168-7
- Short code
- M tb DNA Tiss Ql NAA+probe
- Synonyms
- M tb DNA Tiss Ql NAA+probe
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
How the Test Works
The test involves collecting a sputum sample (usually from coughing into a container) and analyzing it for TB bacteria DNA using advanced molecular techniques. This method is quicker than growing bacteria in a lab, often providing results in days rather than weeks.
Sample Collection
You’ll need to provide a sputum sample, typically from deep coughing. This is usually done in a healthcare setting where you’ll cough into a sterile container. Follow your doctor’s instructions carefully to ensure the sample is representative of your respiratory tract.
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to avoid certain medications or foods that could interfere with the test. If you have a respiratory infection, your doctor may advise waiting until symptoms improve for the most accurate results.
When This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms of TB (like persistent cough, fever, or weight loss), have been exposed to TB, or if you live in an area with higher TB rates. It’s also used to monitor treatment progress or check for recurrence.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
TB DNA Sputum Test
Frequently asked questions
Why was I asked to take this test?
What does a positive result mean?
How long will it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy