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Myeloperoxidase (MPO) Antibody, Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against myeloperoxidase, a protein found in white blood cells. It may help diagnose certain autoimmune conditions or inflammatory diseases.

Quick summary

["This test helps identify immune responses linked to conditions like vasculitis or autoimmune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
71773-6
Short code
M TB IFN-g Bld-Imp
Synonyms
M TB IFN-g Bld-Imp
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What This Test Measures

Myeloperoxidase (MPO) is an enzyme produced by white blood cells called neutrophils. Antibodies against MPO can indicate an immune response, often seen in conditions like vasculitis or certain types of autoimmune diseases. This test detects these antibodies in your serum.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms suggestive of vasculitis (such as skin rashes, kidney problems, or nerve damage) or if you have an autoimmune condition where MPO-related antibodies are suspected.

Preparation for the Test

No special preparation is needed for this test. You may have a blood draw in a clinic or lab, and the sample will be sent to a laboratory for analysis.

What to Expect After the Test

Results from this test are typically reviewed by a healthcare professional to assess your overall health and guide treatment. You may receive results in a few days to a couple of weeks, depending on the lab.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

MPO Antibody Test

Frequently asked questions

What does a positive result mean?
A positive result indicates the presence of MPO antibodies, which may suggest an immune-mediated condition like vasculitis. However, further testing and clinical evaluation are needed to determine the exact cause and appropriate treatment.
Can this test be used to diagnose autoimmune diseases?
While this test can help identify certain autoimmune conditions involving MPO antibodies, it is often used alongside other tests and clinical findings to make a diagnosis. Your doctor will consider the full picture of your symptoms and test results.
How long does it take to get results?
Results typically take between a few days to a couple of weeks, depending on the lab’s processing time. Your healthcare provider will contact you once results are available.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy