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Serum or Plasma Thyroid-Stimulating Hormone (TSH) Measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of TSH, a hormone produced by your pituitary gland that regulates thyroid function. It helps assess whether your thyroid is working properly.

Quick summary

["TSH helps determine if your thyroid is underactive, overactive, or functioning normally."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105758-7
Short code
Mtb mabA ethionmde res mut Islt/S
Synonyms
Mtb mabA ethionmde res mut Islt/S
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a TSH test to check for thyroid problems, such as hypothyroidism (low thyroid activity) or hyperthyroidism (high thyroid activity). It’s often the first test recommended for thyroid function evaluation, especially if you have symptoms like fatigue, weight changes, or mood issues.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood, which usually takes a few minutes. If you’re taking thyroid medication, check with your doctor first to see if you should stop or adjust it before testing.

What the Results Mean

TSH results help guide treatment. Low TSH levels may indicate an overactive thyroid, while high levels suggest an underactive thyroid. Normal results usually fall within a specific range, but your doctor will interpret results in the context of your overall health and symptoms.

Common Reasons for Testing

TSH testing is commonly done if you have symptoms like unexplained weight changes, fatigue, depression, or hair loss. It’s also used to monitor thyroid function after treatment for thyroid disorders or during pregnancy.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: TSH’s Role in Health

Short name

TSH (Thyroid-Stimulating Hormone)

Frequently asked questions

What are the normal reference ranges for this test?
Reference ranges can vary slightly by lab and may not be provided directly on your results. Your doctor will use these values to compare your TSH level to what’s typical for your age, sex, and health status. They’ll also consider your symptoms and medical history to make a diagnosis.
Can I eat or drink before this test?
You can eat and drink normally before this test unless instructed otherwise by your doctor. Avoiding food or fluids for a set period (like fasting) is not required for a TSH blood test.
Will this test affect my thyroid medication?
If you’re taking thyroid replacement medication (like levothyroxine), your doctor may advise temporarily adjusting your dose before testing to get an accurate TSH result. Always follow your healthcare provider’s instructions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy