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Serum or Plasma Mass Concentration of Metanephrines (Catecholamines)

Published: August 9, 2026Updated: August 16, 2026

This test measures the levels of metanephrines, which are breakdown products of adrenaline and noradrenaline, in your blood. They help diagnose conditions affecting your adrenal glands or nervous system.

Quick summary

["Metanephrines can signal potential adrenal gland tumors or nerve system disorders like pheochromocytoma."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
3792-9
Short code
MTX CSF-mCnc
Synonyms
MTX CSF-mCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you have symptoms like high blood pressure, headaches, sweating, rapid heartbeat, or unexplained weight loss. It’s also used to monitor conditions like pheochromocytoma, a rare tumor that can affect hormone production.

What to Expect Before the Test

No special preparation is needed, but you may be asked to avoid certain medications or foods that could affect results, such as caffeine or certain blood pressure medications. Your doctor will provide specific instructions.

What Happens During the Test?

A healthcare provider will draw blood from a vein in your arm. The blood sample is then sent to a lab for analysis. The test usually takes a few minutes, and you may feel slight discomfort but no lasting effects.

What Are the Possible Results?

Results are compared to a reference range provided by your lab. Elevated levels may indicate conditions like pheochromocytoma, while normal levels help rule out these disorders. Your doctor will discuss the results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Metanephrines (Serum/Plasma)

Frequently asked questions

What Does This Test Measure?
Metanephrines are metabolites of adrenaline and noradrenaline, which are hormones produced by the adrenal glands. High levels can suggest tumors (such as pheochromocytoma) or other conditions affecting hormone regulation.
What If My Results Are Abnormal?
If your results are elevated, your doctor may recommend further testing, such as 24-hour urine collection for metanephrines or imaging studies to locate any tumors. Follow-up may include monitoring blood pressure and adjusting medications if needed.
How Often Should I Get This Test?
Your doctor will determine the frequency based on your diagnosis and symptoms. If you have a known condition like pheochromocytoma, tests may be done regularly to check for changes or progression.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy