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Granulocyte Colony-Stimulating Factor (G-CSF) Concentration in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of a protein called granulocyte colony-stimulating factor (G-CSF) in your blood. G-CSF helps stimulate the production of white blood cells, which are important for fighting infections.

Quick summary

["G-CSF helps your body produce more white blood cells to support your immune system."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34628-8
Short code
MTX CSF-sCnc
Synonyms
MTX CSF-sCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have a condition that affects your bone marrow, such as chemotherapy, radiation therapy, or certain blood disorders. It may also be done to monitor treatment responses or side effects, especially if you’re receiving medications that affect white blood cell production.

What to Expect Before the Test

No special preparation is needed for this test. You may have a simple blood draw, where a small needle is used to collect a sample of blood from a vein in your arm. If you’re taking medications that could affect white blood cells, let your healthcare provider know.

What the Test Results Mean

Results can vary depending on your health status and medical history. Low levels might indicate problems with white blood cell production, while higher levels could be seen in certain infections, cancers, or after certain treatments. Your healthcare provider will interpret the results in the context of your overall health.

Common Conditions Monitored

This test is often used to monitor patients undergoing treatments like chemotherapy, bone marrow transplants, or those with conditions like aplastic anemia or certain cancers. It helps track how well your body is responding to treatments that might lower white blood cell counts.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

G-CSF plays a critical role in the production and function of neutrophils, a type of white blood cell that helps fight infections. Abnormal levels can signal underlying health issues, such as infections, bone marrow disorders, or side effects from certain medications. Regular monitoring can help prevent complications and guide treatment decisions.

Short name

G-CSF Level

Frequently asked questions

What does a low G-CSF level mean?
A low G-CSF level may suggest that your bone marrow isn’t producing enough white blood cells, which could be due to conditions like chemotherapy, radiation therapy, or certain blood disorders. It might also indicate an infection or other immune system issues. Your provider will discuss this with you based on your medical history and symptoms.
What causes G-CSF levels to be higher?
Higher G-CSF levels can occur naturally during infections, especially if your body is trying to boost white blood cell production. It may also be seen in certain cancers or after treatments like chemotherapy. If your provider notes elevated levels, they’ll review your treatment plan and overall health to understand the cause.
Is there anything I can do to prepare for this test?
No special preparation is needed, but let your healthcare provider know if you’re taking medications that could affect white blood cells, such as certain chemotherapy drugs or immunosuppressants. Avoiding alcohol or strenuous activity before the test may help, but always follow your provider’s instructions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy