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Total IgE (Immunoglobulin E) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a type of antibody that plays a role in allergic reactions and responses to parasites.

Quick summary

["IgE levels help identify allergies or immune system sensitivities."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61209-3
Short code
Mushroom IgE/IgE total %
Synonyms
Mushroom IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What IgE Does in Your Body

IgE antibodies are part of your immune system’s defense against certain allergens (like pollen, dust, or foods) and parasites. When your body detects these substances, IgE triggers the release of chemicals that cause symptoms like sneezing, itching, or swelling. However, it can also be elevated in conditions like asthma, eczema, or certain infections.

When You Might Need This Test

Your doctor may recommend this test if you have symptoms of allergies (e.g., hives, wheezing, or skin rashes), unexplained asthma, chronic sinusitis, or if you’re being evaluated for conditions like allergic rhinitis or parasitic infections. It can also be used to monitor treatment responses.

How the Test Works

A small blood sample is taken from your arm. The sample is then analyzed in a lab to measure the total IgE concentration. The test doesn’t require fasting and is typically done as part of a routine blood draw.

What to Expect Before the Test

There are no special preparations needed for this test. You can eat, drink, or take medications as usual. If you’re on blood-thinning medications, let your doctor know before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Blood Test

Frequently asked questions

Why might my IgE test result be higher than expected?
Higher IgE levels can be caused by allergies (e.g., to foods, pollen, or pet dander), asthma, eczema, or parasitic infections. Your doctor may also check for other conditions like autoimmune disorders or immune system imbalances. Results alone don’t diagnose a condition—they’re part of a bigger picture.
What does a low IgE level mean?
Low IgE levels are less common and may suggest a reduced allergic response, but they don’t always indicate a problem. Some people naturally have lower IgE, and low levels alone don’t mean you’re at lower risk for allergies. Your doctor will consider your symptoms and other test results.
Can IgE levels change over time?
Yes, IgE levels can fluctuate based on allergies, infections, medications (like antihistamines), or immune system activity. If your levels change significantly, your doctor may retest to understand the cause, such as worsening allergies or treatment responses.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy