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MutY DNA Glycosase Activity in Blood

Published: August 9, 2026Updated: August 16, 2026

This test measures the activity level of the MutY DNA glycosase enzyme in your blood. MutY helps protect your DNA from damage caused by certain types of mutations.

Quick summary

["This test may help assess genetic risks related to DNA repair mechanisms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40959-9
Short code
MUTYH gene Mut Anl Bld/T
Synonyms
MUTYH gene Mut Anl Bld/T
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What Does This Test Measure?

MutY DNA glycosase is an enzyme involved in the cellular process of repairing damaged DNA caused by oxidative stress. Low or altered enzyme activity could indicate potential genetic predispositions to certain conditions.

Why Might You Need This Test?

This test may be ordered as part of genetic screening or research studies focused on DNA repair pathways, particularly in individuals with a family history of genetic disorders or those at higher risk for oxidative DNA damage.

Sample Collection and Preparation

A blood sample is typically collected from a vein in your arm. The sample is processed to isolate cellular components and stored for analysis. This test does not require fasting.

Testing Process

The test measures enzyme activity by detecting its ability to correct specific types of mutations in DNA. Results are compared against a reference range to determine activity levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

MutY Enzyme Activity Test

Frequently asked questions

This test may be relevant in research or specialized clinical settings to understand genetic vulnerabilities related to DNA repair. Abnormal enzyme activity could be associated with inherited conditions affecting DNA repair mechanisms.
This test is not routinely performed for general health screening and may not have widely established reference ranges for clinical decision-making in standard medical practice.
How is the test performed?
The test involves analyzing a blood sample to measure enzyme activity through specialized biochemical methods. Results are interpreted by healthcare providers in the context of your medical history and symptoms.
What do my results mean?
Results may indicate variations in DNA repair capacity, which could be part of broader genetic evaluations. Consult your healthcare provider for personalized interpretation based on your specific situation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy