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Granulocyte Colony-Stimulating Factor (CSF) Level, Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of granulocyte colony-stimulating factor (CSF) in your blood. CSF is a protein that helps stimulate the production of white blood cells, particularly neutrophils, which play a key role in fighting infections.

Quick summary

["CSF supports immune response and helps manage infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88454-4
Short code
MuV IgG+IgM CSF IF-Imp
Synonyms
MuV IgG+IgM CSF IF-Imp
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like frequent or severe infections, low white blood cell counts, or if you’re undergoing treatment that could affect your immune system, such as chemotherapy. It may also be used to monitor certain conditions like bone marrow disorders or after stem cell transplants.

What to Expect Before the Test

No special preparation is typically needed. You may have a blood draw from a vein in your arm, similar to other blood tests. If you’re on blood thinners or have a history of bleeding disorders, let your provider know beforehand.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm. The blood sample will be sent to a lab for analysis. The test measures the concentration of CSF in your serum or plasma using an immunoassay method, which detects the protein’s presence.

What the Results Mean

Results are interpreted by your healthcare provider based on your medical history and symptoms. Abnormal levels may indicate conditions affecting white blood cell production or immune function, but specific interpretations depend on clinical context.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Granulocyte colony-stimulating factor (CSF) is crucial for the production and function of neutrophils, a type of white blood cell that helps fight infections. Low levels may suggest impaired immune response, while elevated levels could indicate inflammation, infection, or certain cancers. Your provider will use these results alongside other tests and symptoms to guide diagnosis and treatment.

Short name

CSF Level

Frequently asked questions

What causes low CSF levels?
Low CSF levels can result from conditions that affect bone marrow function, such as chemotherapy, radiation therapy, or certain blood disorders. It may also occur in people with infections, autoimmune diseases, or after stem cell transplants.
What causes high CSF levels?
Elevated CSF levels are sometimes seen in response to infections, inflammation, or certain cancers (like leukemia). Chronic conditions like rheumatoid arthritis or kidney disease may also play a role, but results depend on the clinical context.
How often should I get this test?
Your provider will determine the frequency based on your medical needs. If you’re undergoing treatment for a condition affecting immune function, follow-up tests may be scheduled regularly to monitor progress or side effects.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy