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C-reactive protein (CRP) concentration, serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a protein produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps identify inflammation, often used to monitor conditions like infections or autoimmune diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
77250-9
Short code
MuV IgG+IgM Pnl Ser
Synonyms
MuV IgG+IgM Pnl Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order a CRP test to check for signs of inflammation, monitor chronic conditions (such as heart disease or arthritis), or evaluate responses to treatments. It can also help diagnose infections or determine if your body is reacting to an injury or illness.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it involves drawing blood from a vein. If you’re taking blood from a finger (capillary blood), no fasting is required.

What Happens During the Test?

A healthcare professional will insert a small needle into a vein in your arm or use a finger-prick method to collect a blood sample. The sample is then sent to a lab for analysis.

What Are Possible Results?

Results are reported in milligrams per deciliter (mg/dL) or micrograms per milliliter (µg/mL). Higher-than-normal levels may indicate inflammation, infections, or other health issues, while lower levels may suggest no active inflammation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CRP (Serum/Plasma)

Frequently asked questions

CRP is a marker of inflammation and can help diagnose or monitor conditions like rheumatoid arthritis, heart disease, or infections. It’s also used to assess how well a treatment is working or to screen for early signs of disease progression.
What does a high CRP level mean?
A high CRP level often signals inflammation in your body, which can be caused by infections (like pneumonia or urinary tract infections), autoimmune diseases (such as lupus or rheumatoid arthritis), or other inflammatory conditions. Your doctor will consider your symptoms and other test results to determine the cause.
What does a low CRP level mean?
A low CRP level typically means there is little to no inflammation detected in your blood. However, it doesn’t rule out all causes of inflammation, so your doctor may still recommend further testing if needed.
Yes, lifestyle factors like diet, exercise, and stress can influence CRP levels. Eating a healthy diet, staying active, and managing stress may help lower inflammation over time, but results may take weeks or months to show.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy