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Serum or Plasma Mass Concentration of Vitamin K-Dependent Carboxylated Proteins (MCP)

Published: August 9, 2026Updated: August 16, 2026

This test measures specific proteins in your blood that rely on vitamin K for proper function. These proteins help with blood clotting and other important processes in your body.

Quick summary

["Assesses vitamin K-dependent protein status, which supports blood clotting and metabolic functions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13267-0
Short code
MuV IgM CSF-aCnc
Synonyms
MuV IgM CSF-aCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have concerns about vitamin K deficiency, bleeding disorders, liver disease, or if you’re taking medications that affect vitamin K levels. It may also be used to monitor treatment for conditions like osteoporosis or certain blood clotting disorders.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it involves drawing blood from a vein. If you’re taking blood thinners, inform your provider beforehand.

What the Test Involves

A healthcare professional will draw blood from a vein in your arm. The blood sample is then sent to a lab for analysis. The test measures the mass concentration of certain proteins in your serum or plasma.

What the Results Mean

Results help determine if your vitamin K-dependent proteins are functioning normally. Low levels may indicate vitamin K deficiency, liver issues, or other health concerns. Your provider will discuss the results with you in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin K-dependent proteins, such as proteins C, S, and Z, play critical roles in blood clotting and bone metabolism. Abnormal levels can signal bleeding risks, liver dysfunction, or vitamin K deficiency. Monitoring these proteins helps guide treatment for conditions like anticoagulant therapy or inherited clotting disorders.

Short name

Vitamin K-dependent protein levels

Frequently asked questions

What causes abnormal vitamin K-dependent protein levels?
Abnormal levels may result from vitamin K deficiency (due to poor diet, liver disease, or medications like antibiotics), liver problems, or conditions affecting protein synthesis. Chronic kidney disease or certain genetic disorders can also influence these levels.
How are these results used to guide treatment?
Your provider may adjust medications (like blood thinners) or recommend dietary changes (such as increasing vitamin K-rich foods) if levels are low. If high, they may investigate underlying causes like liver disease or overmedication.
Can lifestyle changes affect this test?
Yes—dietary changes (e.g., more leafy greens for vitamin K) or avoiding certain medications (like broad-spectrum antibiotics) may impact results. Always discuss lifestyle adjustments with your healthcare team before making changes.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy