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Granulocyte Colony-Stimulating Factor (CSF) – Serum or Plasma Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of granulocyte colony-stimulating factor (CSF) in your blood. CSF is a protein that helps stimulate the production of white blood cells, particularly neutrophils, which play a key role in fighting infections.

Quick summary

["CSF supports immune response and helps diagnose or monitor conditions affecting white blood cell production."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
41131-4
Short code
MuV IgM CSF Ql
Synonyms
MuV IgM CSF Ql
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

What Is Granulocyte Colony-Stimulating Factor (CSF)?

Granulocyte colony-stimulating factor (CSF) is a protein produced naturally in the body. It encourages the bone marrow to produce more neutrophils, a type of white blood cell that helps fight infections. Low levels may indicate problems with blood cell production or immune function.

Why Might You Need This Test?

Doctors may order this test to evaluate conditions like bone marrow disorders, chemotherapy-related neutropenia (low neutrophil count), or infections. It can also help monitor treatment responses in cancer or other diseases affecting white blood cells.

When Is This Test Performed?

This test is typically drawn from a blood sample collected in a serum or plasma tube. Results are often used alongside other blood tests to assess overall immune function or specific blood cell counts.

What Does a Low or High CSF Level Mean?

Interpretation depends on clinical context. Very low levels may suggest impaired bone marrow function or certain cancers, while elevated levels could indicate inflammation or other systemic conditions. Your doctor will review results with your symptoms and other test results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CSF Level

Frequently asked questions

Why was I asked to have this test?
Your doctor may recommend this test if you have symptoms like frequent infections, fatigue, or if you’re undergoing treatment that affects white blood cell production (e.g., chemotherapy). It helps assess whether your body is producing enough neutrophils to fight infections effectively.
What do my test results mean?
Your results will be discussed with your healthcare provider, who will consider your medical history, symptoms, and other tests. They’ll explain whether the level is within expected ranges or if it suggests a need for further evaluation.
How long will it take to get my results?
Results are usually available within 1–3 business days, depending on lab processing times. Your doctor will contact you once they’re ready for review.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy