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Vitamin D Binding Protein (DBP) or Discriminating Binding Protein (DBP) – Serum Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Vitamin D Binding Protein in your blood, which helps transport vitamin D and other hormones. It may be used alongside vitamin D levels to assess overall vitamin D status.

Quick summary

["Your DBP levels can help doctors understand how well your body is using vitamin D and other substances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22420-4
Short code
MuV IgM Titr Ser
Synonyms
MuV IgM Titr Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if they suspect conditions affecting vitamin D metabolism, hormone transport, or kidney function. It could also be part of a broader evaluation for hereditary disorders like hypophosphatasia or certain metabolic syndromes.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re on blood thinners or have a history of bleeding disorders, let your provider know before the test.

What the Results Mean

While DBP levels alone don’t directly indicate vitamin D deficiency, they can help assess how your body processes vitamin D and other hormones. Abnormal levels might suggest genetic conditions or kidney-related issues.

Common Conditions Monitored

This test may be used to evaluate conditions like hereditary vitamin D-resistant rickets, certain kidney diseases, or metabolic disorders affecting hormone binding.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Elevated DBP levels can occur in kidney disease or certain genetic disorders, while very low levels may suggest hereditary conditions. It’s often used in conjunction with vitamin D testing to refine diagnosis and treatment planning.

Short name

DBP Level

Frequently asked questions

What causes abnormal DBP levels?
Abnormal DBP levels may result from genetic mutations, kidney disease, or metabolic disorders. Your provider will consider your full medical history and other test results to determine the cause.
How often should I get this test?
Your provider will determine the frequency based on your health needs. Some patients may need it yearly, while others may require it less often depending on their condition.
Does diet affect DBP levels?
Dietary factors like vitamin D intake may indirectly influence hormone transport, but DBP itself is primarily regulated by genetics and kidney function. Your provider can clarify if lifestyle changes are recommended.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy