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Serum Creatinine (Creatinine Level)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess how well your kidneys are filtering blood.

Quick summary

["Kidney function check: creatinine levels help determine if your kidneys are working properly."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
80054-0
Short code
MV lat ann e-prime Vmax TDI.A4C
Synonyms
MV lat ann e-prime Vmax TDI.A4C
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
us-tissue-doppler-a-c
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is normally filtered out by your kidneys. High levels can indicate kidney problems, while low levels may suggest dehydration or muscle loss. This test is often used alongside other measures like blood urea nitrogen (BUN) to evaluate kidney function.

What to Expect Before the Test

You may be asked to fast for a few hours before your blood is drawn, though this is not always required. Drink plenty of water the day before if you suspect dehydration. Avoid strenuous exercise or heavy meals before testing.

What to Expect During the Test

A healthcare professional will insert a small needle into a vein in your arm to draw a blood sample. You may feel a brief pinch, but it usually doesn’t cause significant discomfort. The process takes just a few minutes.

What the Results Mean

Results are typically reported in milligrams per deciliter (mg/dL) or micromoles per liter (µmol/L). While reference ranges vary by lab, higher than expected levels may signal kidney issues, while very low levels might warrant further investigation for conditions like muscle wasting or severe dehydration.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Creatinine levels are a key indicator of kidney function. Chronic kidney disease (CKD) is often detected early through elevated creatinine, as it reflects how well your kidneys are removing waste. Doctors may also use creatinine to monitor kidney health in people with diabetes, hypertension, or other risk factors. Repeated tests can help track progression or response to treatment.

Short name

Creatinine

Frequently asked questions

What causes creatinine levels to change?
Creatinine levels can be affected by muscle mass (higher muscle = higher creatinine), dehydration, kidney disease, or certain medications. Conditions like heart failure or severe infections may also influence results. If you’ve had recent surgery, trauma, or changes in diet, let your doctor know.
How often should I get this test?
Your doctor will determine how often you need this test based on your health history, symptoms, and risk factors. For example, people with diabetes or kidney disease may need it more frequently than others. Follow-up tests are often scheduled if you have chronic conditions or if your results are outside normal ranges.
Can diet or exercise affect creatinine levels?
Yes, diet (especially protein intake) and exercise can influence creatinine levels. High-protein diets may temporarily raise levels, while dehydration or intense exercise can lower them. Avoiding excessive protein or staying hydrated can help stabilize results. Always discuss dietary changes with your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy