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Serum or plasma measurement of total protein concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of protein in your blood, which helps assess overall health, hydration, and potential protein-related conditions.

Quick summary

["Total protein levels can signal hydration status, liver/kidney function, or nutritional needs."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
103630-0
Short code
MVPX IgM Titr Ser IA
Synonyms
MVPX IgM Titr Ser IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why It’s Done

Your healthcare provider may order this test to check for conditions like dehydration, liver disease, kidney problems, or malnutrition. It’s also used to monitor treatment responses in certain conditions.

What to Expect

A small blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab where it’s analyzed to determine protein concentration.

Normal vs. Abnormal Results

While reference ranges vary by lab, higher-than-expected levels may indicate conditions like multiple myeloma or severe dehydration. Lower-than-expected levels could signal liver disease, kidney problems, or malnutrition.

Common Conditions Affecting Results

Changes in total protein can reflect broader health issues, such as fluid balance problems, organ dysfunction, or dietary deficiencies.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein

Frequently asked questions

What might cause my total protein test result to be different than expected?
Several factors can influence results, including dehydration or overhydration, liver or kidney disease, certain medications, or chronic conditions like cancer. Your provider may also consider your medical history and symptoms when interpreting the result.
How often should I get this test?
Frequency depends on your health status and why the test was ordered. Routine adults typically don’t need this test unless recommended by a doctor for monitoring a specific condition.
Can diet affect my protein levels?
Yes, diet can impact protein levels. High-protein diets may temporarily raise levels, while poor nutrition or certain medical conditions can lower them. Always follow your provider’s guidance on dietary considerations related to this test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy