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Serum or Plasma Creatinine Concentration (Substance Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of creatinine, a waste product from muscle metabolism, in your blood. It helps assess kidney function.

Quick summary

["A creatinine test helps check how well your kidneys filter waste from your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
103628-4
Short code
MVPX NAb Titr Ser IA
Synonyms
MVPX NAb Titr Ser IA
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Creatinine is a byproduct of muscle breakdown and is normally filtered out by your kidneys. High levels may indicate kidney problems, while low levels could suggest dehydration or muscle loss. This test is often used alongside other kidney function tests to monitor overall kidney health.

What to Expect Before the Test

No special preparation is needed for this test. You may drink water before the test, but avoid excessive fluids unless instructed otherwise. If you’re on a low-protein diet, follow your doctor’s advice, as protein intake can affect creatinine levels.

How the Test Is Performed

A blood sample is drawn from a vein, usually in your arm, using a small needle. You may feel a slight pinch, but it usually doesn’t cause discomfort. The sample is then sent to a lab for analysis.

Possible Results and Interpretation

Results are compared to a reference range that varies by lab and individual factors like age, sex, and muscle mass. Elevated creatinine levels may signal impaired kidney function, while persistently low levels could warrant further investigation for conditions like malnutrition or dehydration.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Creatinine Level

Frequently asked questions

What does my creatinine level tell me about my health?
High creatinine levels often point to kidney disease, where the kidneys struggle to remove waste efficiently. Your doctor may recommend follow-up tests or adjustments to medications if levels are elevated. Always discuss results with your healthcare provider, as they’ll consider your full medical picture.
Can diet or exercise affect my creatinine test results?
Yes, diet—especially protein intake—can influence creatinine levels. High-protein foods may temporarily raise levels, while dehydration can lower them. Exercise itself doesn’t directly affect creatinine, but it may indirectly impact kidney function if overdone. Ask your doctor about any dietary or lifestyle adjustments.
How often should I get this test?
Frequency depends on your health. People with kidney disease may need tests more often, while healthy individuals might only get this test as part of routine check-ups or when symptoms arise (e.g., fatigue, swelling, or changes in urine). Follow your doctor’s recommendations.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy