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Mycobacterium tuberculosis Antigen Detection (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of Mycobacterium tuberculosis antigens in your blood, which may indicate an active tuberculosis (TB) infection.

Quick summary

["Helps diagnose TB by detecting specific proteins from the bacteria in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
76687-3
Short code
Mycobacterium BAL Cult
Synonyms
Mycobacterium BAL Cult
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test identifies Mycobacterium tuberculosis antigens—specific proteins produced by the bacteria that cause TB. These proteins are released into your blood when the infection is active. This method helps confirm TB before symptoms appear or when other tests are inconclusive.

Why It Might Be Ordered

Your healthcare provider may order this test if you have symptoms of TB (such as fever, cough, or weight loss), if you’ve been exposed to TB, or if you have a weakened immune system. It’s also used in screening for TB in certain high-risk groups.

How the Test Works

Blood is drawn and analyzed using an immunoassay (a lab test that detects specific proteins) to detect the presence of TB antigens. The result is qualitative, meaning it only tells whether the antigens are present or not.

What to Expect Before the Test

No special preparation is needed. You may have a slight bruise or soreness at the injection site, but this is normal. Avoid alcohol or certain medications (like blood thinners) before the test if instructed by your provider.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result strongly suggests an active TB infection and should prompt immediate medical evaluation and treatment. A negative result means no detectable antigens were found, but TB could still be present in early or latent stages. Follow-up testing or additional evaluations may be needed based on clinical findings and exposure history.

Short name

TB Antigen Test

Frequently asked questions

How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times.
What does a positive result mean?
A positive result indicates the presence of TB antigens in your blood, which strongly suggests an active TB infection. Your doctor will work with you to determine the next steps, including further testing or starting treatment.
Can this test detect latent TB?
No, this test specifically detects active TB infection by measuring antigens. For latent TB, a different test (like a TB skin test or interferon-gamma release assay) is typically used.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy