Mycobacterium DNA in Bronchial Lavage Fluid by Nucleic Acid Amplification Probe

What This Test Measures

The test looks for DNA fragments from *Mycobacterium* bacteria in fluid collected from your lungs (bronchial lavage). These DNA fragments are detected using a specialized probe that targets genetic sequences unique to these bacteria. This method is highly sensitive and can identify even small amounts of bacterial DNA.

Why It’s Used

This test is often used when doctors suspect a lung infection caused by *Mycobacterium* species, such as tuberculosis (TB) or atypical mycobacterial infections. It may be recommended if you have persistent cough, fever, or other symptoms of lung infection, especially if standard tests like cultures are slow or inconclusive.

Sample Collection and Process

A sample is collected by inserting a tube into your airway to collect fluid from your lungs. This fluid is then processed in the lab to extract and analyze the bacterial DNA. The test does not require fasting or special preparation beyond standard lab procedures.

Limitations and Considerations

While this test is very sensitive, it may not always detect *Mycobacterium* DNA if the infection is very recent or if the bacteria are present in very low numbers. False positives can rarely occur, so results should always be reviewed by your healthcare provider in the context of your symptoms and medical history.