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Mycobacterium DNA Nucleic Acid Probe (Urinalysis)

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from *Mycobacterium* species, including potential tuberculosis or nontuberculous mycobacteria, in your urine. It helps diagnose infections when other tests may be inconclusive.

Quick summary

["This test may help identify urinary tract infections caused by *Mycobacterium* bacteria, including tuberculosis or other mycobacterial strains."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30523-5
Short code
Mycobacterium DNA Ur Ql NAA+probe
Synonyms
Mycobacterium DNA Ur Ql NAA+probe
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

This test measures the level of a specific substance in your body, such as a protein, hormone, or marker of infection or inflammation, giving your healthcare provider important information about how your body is functioning and whether any area needs closer attention.

The test uses a specialized probe to detect the presence of *Mycobacterium* DNA fragments in your urine. This genetic material can be shed by infected bacteria, allowing for early detection if present. The probe targets conserved regions of the bacterial genome to ensure accuracy across different *Mycobacterium* species.

Your doctor may order this test if you have symptoms that suggest a possible infection or other medical condition, if you are being monitored for an ongoing health problem, or as part of a routine checkup to screen for disease before symptoms appear.

Your healthcare provider may recommend this test if you have symptoms like persistent fever, unexplained weight loss, or urinary symptoms (such as pain or frequent urination) that suggest a *Mycobacterium* infection, especially if other tests (like cultures) have been negative or delayed. It’s also useful in monitoring patients with known mycobacterial exposure.

The test works by analyzing a small sample taken from your body in a certified laboratory, where trained technicians use specialized instruments to detect and measure the substance of interest and report an accurate result that your provider interprets along with your medical history and symptoms.

The test involves collecting a urine sample, which is then analyzed using molecular techniques (like nucleic acid amplification) to identify *Mycobacterium* DNA. Unlike traditional cultures, this method provides results faster and can detect bacteria even when they are in low numbers.

Preparation is usually simple, but follow any instructions your provider gives you, such as fasting or avoiding certain medicines beforehand. A sample of blood, urine, or another body fluid is collected in a sterile container or tube, a quick process that may cause only brief, mild discomfort.

No special preparation is needed for this test. You’ll provide a midstream urine sample (collecting urine midstream into a sterile container) or a timed urine specimen, depending on your provider’s instructions. Avoid using sanitizers or cleaning agents that may interfere with the test results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Mycobacterium DNA Probe (Urine)

Frequently asked questions

This test is particularly useful for diagnosing urinary tract infections caused by *Mycobacterium tuberculosis* (the bacterium responsible for tuberculosis) or other *Mycobacterium* species, which can sometimes cause chronic or persistent infections. It helps rule out or confirm infections in patients with atypical symptoms or negative cultures, reducing unnecessary delays in treatment.
How soon will my test results be ready, and how will my healthcare provider share them with me?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your healthcare provider will discuss the results with you during your follow-up visit.
Should I avoid taking antibiotics before this test, and how long should I wait after finishing a course of them?
Yes, you may have already been prescribed antibiotics, but inform your healthcare provider before the test. If you’re unsure, ask them whether to stop or adjust your medication temporarily to avoid interfering with the test results.
A positive result indicates the presence of *Mycobacterium* DNA in your urine, suggesting an infection. Your provider will work with you to determine the next steps, which may include additional testing (like cultures), further imaging, or a tailored treatment plan based on the specific *Mycobacterium* species identified.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy