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: Mycobacterium species Identification by Sequencing

Published: August 9, 2026Updated: August 16, 2026

: This test uses molecular sequencing to identify which species of Mycobacterium is present in a sample. It helps distinguish tuberculosis-causing organisms from other, often less harmful, mycobacteria.

Quick summary

[": Sequencing provides a precise species-level identification of Mycobacterium that guides treatment decisions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9825-1
Short code
Mycobacterium Islt
Synonyms
Mycobacterium Islt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What This Test Does

: The test reads genetic material (DNA) from a mycobacterium in your sample and compares it to known reference sequences. This allows the laboratory to name the exact species rather than just confirming that some mycobacterium is present.

: Why Species Identification Matters

: Different mycobacteria require very different treatments. Members of the Mycobacterium tuberculosis complex need specific antibiotic regimens, while many non-tuberculous mycobacteria are handled differently or may not need treatment at all. Knowing the species helps your care team choose the right approach.

: How the Sample Is Collected

: The sample depends on where the infection is suspected and may include sputum, other respiratory specimens, tissue, or fluid. Your provider will explain how your particular sample will be collected. Molecular testing is often run on a specimen that has already shown mycobacteria by another method.

: What Results Mean

: A result names the species or group detected, which your provider interprets alongside your symptoms, imaging, and other tests. A result that does not identify a species, or that is negative, does not by itself rule infection in or out and is interpreted in context.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

: Species-level identification of mycobacteria is clinically important because it separates tuberculosis from non-tuberculous mycobacterial disease, informs whether treatment is needed, and guides selection of an appropriate antimicrobial regimen. Sequencing is especially useful when conventional testing cannot clearly distinguish closely related species.

Short name

: NONE

Frequently asked questions

: Is this the same as a tuberculosis test?
: Not exactly. It can identify organisms in the tuberculosis complex, but it also identifies many other mycobacterial species. It is often used alongside, not instead of, other tuberculosis testing.
: Does a result mean I definitely have an infection?
: The test detects and identifies mycobacterial genetic material in the sample provided. Whether that represents active infection depends on your symptoms and other findings, so your provider interprets the result in context.
: Will I get a numeric reference range with this result?
: No. This is an identification test, so results are reported as the species or organism group detected rather than as a number compared with a reference range.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy