Mycobacterium tuberculosis-specific Latex Agglutination Test (LAT) or Tuberculosis (TB) Serology (IgG) – High-Performance Liquid Chromatography (Hplc) Method
This test measures antibodies in your blood that may indicate past exposure to *Mycobacterium tuberculosis*, the bacterium responsible for tuberculosis (TB). It is not a direct test for active TB but can help assess immune response to the infection.
["This test helps determine if your body has recognized *Mycobacterium tuberculosis* and produced antibodies, which may suggest prior exposure or infection (even if no active symptoms exist)."]
Key facts at a glance
- LOINC
- 67725-2
- Short code
- Mycobacterium Islt HPLC
- Synonyms
- Mycobacterium Islt HPLC
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- hplc
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects specific antibodies (IgG) produced by your immune system in response to *Mycobacterium tuberculosis*. These antibodies are part of your body’s defense against the bacterium. The presence of these antibodies does not confirm active TB but can indicate past exposure or infection. The test uses a high-performance liquid chromatography (Hplc) method to analyze serum or plasma samples for these antibodies.
Why It Might Be Ordered
Your healthcare provider may order this test if you have a history of TB exposure, live in a region with higher TB rates, or have symptoms that could suggest TB (e.g., persistent cough, fever, weight loss). It may also be used in screening or monitoring for latent TB infection in certain populations.
What to Expect Before the Test
No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood. If you are on blood-thinning medications or have a bleeding disorder, let your provider know before the test. Avoid alcohol before testing if instructed, as it may affect blood chemistry results indirectly.
What to Expect During the Test
The blood sample is collected in a tube and sent to a lab for analysis. The Hplc method separates and measures the antibody components in your serum or plasma. Results are typically reported as positive, negative, or indeterminate, depending on antibody levels detected.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
TB Serology (IgG) – Hplc
Frequently asked questions
How long does it take to get results?
What does a positive result mean?
Can this test be used to diagnose active TB?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy