Mycobacterium tuberculosis Antigen Detection (in Specimen)
This test detects specific antigens from *Mycobacterium tuberculosis*, the bacterium responsible for tuberculosis (TB). It helps identify active TB infection in your body.
["This test can help diagnose active TB by detecting bacteria-related proteins in your specimen."]
Key facts at a glance
- LOINC
- 40699-1
- Short code
- Mycobacterium Spec
- Synonyms
- Mycobacterium Spec
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
How the Test Works
The test analyzes a sample of your bodily fluid (such as blood, urine, or other fluids) for the presence of *Mycobacterium tuberculosis* antigens. These antigens are proteins released by the bacteria during active infection. The test uses a sensitive detection method to identify these proteins, which can confirm or help rule out TB.
What to Expect Before the Test
No special preparation is needed for this test. You may be asked to provide a sample (e.g., urine, blood, or other fluid) depending on your clinical situation. If you’re unsure about the type of specimen, discuss it with your healthcare provider.
Common Uses of This Test
This test is primarily used to diagnose **active tuberculosis (TB)** in people who have symptoms like persistent cough, fever, weight loss, or chest pain. It may also be used in screening or monitoring for TB in high-risk groups (e.g., immunocompromised individuals, healthcare workers).
Potential Limitations
While this test is highly sensitive, it may not detect all cases of TB, especially in early or latent stages. False negatives can occur if the infection is very recent or if the specimen is not collected properly. Results should always be interpreted by a healthcare provider in the context of your symptoms and medical history.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
TB Antigen Test
Frequently asked questions
Why might my healthcare provider order this test?
What does a positive result mean?
What if I have a negative result but still suspect TB?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy