Mycobacterium Species Detection by Sequencing (Genomic DNA)
This test identifies specific genetic material from *Mycobacterium* bacteria, which can help diagnose infections like tuberculosis or other mycobacterial diseases.
["It helps confirm or rule out certain bacterial infections based on genetic evidence."]
Key facts at a glance
- LOINC
- 90306-2
- Short code
- Mycobacterium Spec Seq
- Synonyms
- Mycobacterium Spec Seq
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- sequencing
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test analyzes genetic material (DNA) from *Mycobacterium* species, which may include common pathogens like *Mycobacterium tuberculosis* (the cause of tuberculosis) or other atypical mycobacteria. This method detects unique genetic sequences associated with these bacteria, allowing for precise identification even if cultures take longer to grow.
Why It’s Used
Doctors may order this test when symptoms like persistent cough, fever, or weight loss suggest a possible *Mycobacterium* infection, especially in people with weakened immune systems, recent travel to high-risk areas, or exposure to known cases.
Sample Collection and Processing
The test typically uses a sample from a bodily fluid or tissue (e.g., sputum, blood, or other clinical specimens) where *Mycobacterium* bacteria may be present. The DNA is extracted and sequenced to identify matching genetic markers.
Limitations and Considerations
While highly specific, this test may not detect all *Mycobacterium* species or detect low-level infections if the sample lacks sufficient genetic material. Results may take several days to weeks, depending on lab workflows.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Mycobacterium DNA Sequencing
Frequently asked questions
This test plays a critical role in diagnosing hard-to-treat infections by providing faster and more accurate results than traditional culture methods. Early detection can guide appropriate treatment, including antibiotics or other therapies tailored to the identified pathogen.
Results can take anywhere from a few days to over a week, depending on lab processing times and specimen availability. Your healthcare provider will discuss timelines with you during follow-up.
This test focuses on detecting specific genetic sequences of *Mycobacterium* species, including some common pathogens like *M. tuberculosis*. However, it may not identify all possible strains or atypical mycobacteria without further confirmation.
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy