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Mycoplasma pneumoniae Antibody, Serum (Qualitative Immunoassay)

Published: August 9, 2026Updated: August 16, 2026

This test detects antibodies to *Mycoplasma pneumoniae*, a bacteria that can cause respiratory infections like pneumonia or bronchitis. It helps diagnose infections when symptoms persist or culture results are unavailable.

Quick summary

["This test may be used if you have unexplained lung or respiratory symptoms, especially after exposure to respiratory illnesses."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22428-7
Short code
Mycoplasma Ab Ser Ql
Synonyms
Mycoplasma Ab Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

When Is This Test Ordered?

Your healthcare provider may recommend this test if you have symptoms like persistent cough, fever, or chest pain that don’t improve with typical antibiotics. It’s often used in cases where other tests (like cultures) haven’t confirmed the infection or when symptoms suggest *Mycoplasma* as the likely cause.

What Does a Positive Result Mean?

A positive result indicates the presence of antibodies against *Mycoplasma pneumoniae*, suggesting past or current infection. However, antibodies may take weeks to develop, so a negative result doesn’t always mean the infection is absent.

What Does a Negative Result Mean?

A negative result means no detectable antibodies were found in this sample, which could mean the infection is not active or has already resolved. It doesn’t rule out *Mycoplasma* infection entirely, especially if symptoms are recent.

How Is This Test Performed?

A blood sample is drawn from a vein in your arm. The serum (liquid part of blood) is then tested using an immunoassay method to detect specific antibodies against *Mycoplasma pneumoniae*. Results are qualitative (positive/negative) rather than quantifiable.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Mycoplasma Ab Serology

Frequently asked questions

Why was this test ordered?
Your doctor may have ordered this test to investigate persistent or atypical respiratory symptoms, rule out *Mycoplasma* infection in cases of unexplained pneumonia, or guide treatment decisions when other tests are inconclusive.
What does a positive result tell me about my health?
A positive result suggests *Mycoplasma pneumoniae* infection may have occurred, but it doesn’t confirm the current cause of your symptoms. Antibodies can take time to develop, so a single negative result doesn’t always mean the infection is absent. Follow-up testing or other diagnostic methods may be needed.
Can I get this test at home?
No, this test requires a blood sample collected by a healthcare professional in a clinical setting. Home testing kits for antibody detection are not FDA-approved for this specific purpose.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy