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Mycoplasma pneumoniae DNA Detection by Nucleic Acid Probe (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for genetic material from *Mycoplasma pneumoniae*, a common bacteria that sometimes causes respiratory infections like pneumonia or bronchitis. It helps determine if you’ve been exposed to this bacteria.

Quick summary

["This test may help diagnose infections caused by *Mycoplasma pneumoniae* in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
46111-1
Short code
Mycoplasma DNA Fld Ql NAA+probe
Synonyms
Mycoplasma DNA Fld Ql NAA+probe
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like persistent cough, fever, or chest pain that don’t improve with usual antibiotics. It’s also used in cases where other tests for infections aren’t clear-cut.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample (either serum or plasma) via a simple venipuncture. The sample is then tested for genetic material specific to *Mycoplasma pneumoniae*.

What the Test Results Mean

A positive result means the test detected genetic material from *Mycoplasma pneumoniae*, suggesting recent exposure or infection. A negative result means the bacteria’s genetic material wasn’t found in your sample.

Possible Limitations

This test can’t distinguish between active infection and past exposure. It may also give false positives or negatives, especially if you’ve recently taken antibiotics or have other infections.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Mycoplasma pneumoniae is a tricky bacteria because it doesn’t grow in traditional culture labs. This test provides a direct, sensitive way to detect it quickly, which is especially useful in diagnosing atypical pneumonia or respiratory infections in adults. Early identification can guide treatment decisions, such as targeting antibiotics that work against this specific bacteria.

Short name

Mycoplasma pneumoniae DNA Test

Frequently asked questions

What does a positive result mean for my health?
A positive result indicates that genetic material from *Mycoplasma pneumoniae* was found in your sample. This suggests you may have been infected recently, but it doesn’t confirm the bacteria is causing symptoms. Your doctor will consider symptoms, medical history, and other test results to determine the next steps, such as starting appropriate treatment.
Can this test be affected by antibiotics I’ve taken?
Yes, antibiotics can interfere with this test. If you’ve recently taken antibiotics, it’s possible the test could show a false negative because the bacteria’s genetic material may have been destroyed. Your doctor may recommend waiting a few days after stopping antibiotics before retesting.
How long does it take to get results from this test?
Results are typically available within 24 to 48 hours, depending on your lab’s processing schedule. Your healthcare provider will contact you once the results are ready, so keep their contact information handy.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy