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Mycoplasma DNA Detection by Nucleic Acid Amplification Probe (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for genetic material from certain bacteria called *Mycoplasma*, which can sometimes cause infections. It uses a specialized probe to detect DNA from these bacteria in your blood.

Quick summary

["Helps identify possible infections by *Mycoplasma* that may require treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
23301-5
Short code
Mycoplasma DNA Spec Ql NAA+probe
Synonyms
Mycoplasma DNA Spec Ql NAA+probe
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects the presence of *Mycoplasma* DNA in your blood using a molecular probe. This method is highly sensitive and can identify even small amounts of genetic material from these bacteria, which may indicate an infection.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fever, fatigue, or respiratory issues, especially if other tests for common infections have come back negative. It’s also used in cases where *Mycoplasma* is suspected as a cause of persistent symptoms.

How the Test Works

The test involves collecting a blood sample (serum or plasma) and analyzing it for *Mycoplasma* DNA. A probe specifically designed to match the genetic sequence of *Mycoplasma* binds to any DNA present, allowing the test to detect the infection.

Preparation for the Test

No special preparation is needed. You may eat or drink normally before the blood draw. If you’re on blood-thinning medications, let your provider know before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Mycoplasma DNA Test

Frequently asked questions

What does a positive result mean?
A positive result suggests the presence of *Mycoplasma* DNA in your blood, which may indicate an active infection. This could be linked to conditions like chronic fatigue syndrome, certain lung diseases, or other systemic symptoms. Further testing and medical evaluation will be needed to determine the best course of action.
What does a negative result mean?
A negative result means no detectable *Mycoplasma* DNA was found in your sample at this time. However, it’s possible the infection is still present but at very low levels, or the infection may have cleared. Follow-up testing or additional symptoms may guide further investigation.
How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your healthcare provider will discuss the results with you during your follow-up visit.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy