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Mycoplasma pneumoniae Detection by Fluorescent Antibody Test (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for antibodies to *Mycoplasma pneumoniae*, a common bacteria linked to respiratory infections like pneumonia and bronchitis. It helps determine if your immune system has encountered this organism.

Quick summary

["This test may be used to diagnose infections caused by *Mycoplasma pneumoniae* when other tests are inconclusive or symptoms persist."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34702-1
Short code
Mycoplasma Spec Ql Hoechst Stn
Synonyms
Mycoplasma Spec Ql Hoechst Stn
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Ref low
1.5
Ref high
9
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
hoechst-stain
CPT
83002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects specific antibodies (immunoglobulins) produced by your immune system in response to *Mycoplasma pneumoniae*. These antibodies appear in your blood after exposure to the bacteria. The presence of these antibodies suggests past or current infection, though they may take several days to weeks to develop.

How the Test Works

This is a fluorescent antibody test, meaning a fluorescent dye is used to identify antibodies bound to *Mycoplasma pneumoniae* antigens in your serum or plasma. The test is qualitative, meaning it provides a yes/no result rather than a quantitative measurement of antibody levels.

When You Might Need This Test

Your healthcare provider may order this test if you have symptoms like cough, fever, or chest pain that suggest a respiratory infection, especially if other tests (like a chest X-ray or culture) are unclear. It’s often used in cases where *Mycoplasma pneumoniae* is suspected but not confirmed by other methods.

What to Expect Before the Test

No special preparation is needed for this test. You’ll provide a blood sample, typically drawn from a vein in your arm. The sample is then processed in the lab to detect antibodies.

Reference range

Follicular: 1.5-9.0 mIU/mLN/A

Specimen: plasma

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate exposure to *Mycoplasma pneumoniae*, which can cause mild to severe respiratory illness. While this test helps diagnose infection, it does not confirm active disease in all cases. Antibody levels may remain positive for months or years after infection. This test is particularly useful for diagnosing atypical pneumonia or persistent coughs in adults and children.

Short name

Mycoplasma pneumoniae Antibody Screen

Frequently asked questions

How long does it take to get results from this test?
Results are usually available within 1–3 business days, depending on your lab’s processing schedule. Your healthcare provider will discuss the results with you during your follow-up visit.
Can I have this test if I’m pregnant?
Yes, this test is generally safe to perform during pregnancy. However, your healthcare provider will consider the potential benefits and risks based on your specific situation and may recommend alternative tests if needed.
What if my test comes back positive but I don’t feel sick?
A positive result means your body has detected antibodies to *Mycoplasma pneumoniae*, which could indicate past exposure. You may not have active symptoms now, but your provider may monitor you for potential future complications or recommend further testing if needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy