Skip to content

: Myeloid-to-Erythroid Cell Ratio

Published: August 9, 2026Updated: August 16, 2026

: The myeloid-to-erythroid ratio is a calculation made from a bone marrow examination that compares the number of myeloid cells to erythroid cells.

Quick summary

[": The M:E ratio helps your care team understand the balance of white blood cell precursors and red blood cell precursors in the bone marrow."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
11138-5
Short code
Myeloid cells/Erythroid Cells Mar
Synonyms
Myeloid cells/Erythroid Cells Mar
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

: What This Test Measures

: During a bone marrow examination, a specialist examines a sample under a microscope and classifies the cells they see. Myeloid cells are precursors of certain white blood cells, while erythroid cells are precursors of red blood cells. The ratio compares the count of myeloid cells to erythroid cells.

: Why It Is Ordered

: This ratio is typically part of a broader bone marrow evaluation. It may be used when a blood count is abnormal, when a blood disorder is suspected, or to help monitor a known condition affecting the bone marrow.

: How the Sample Is Collected

: The ratio is determined from a bone marrow sample, usually obtained by a bone marrow aspiration and sometimes a biopsy. These procedures are performed by a clinician and the sample is examined in a laboratory.

: What the Result Can Mean

: A ratio that falls outside the expected range can reflect an increase or decrease in one cell line. However, the ratio is only one part of the overall picture and is interpreted together with cell appearance, blood counts, and other findings. Your care team will explain what your result means in context.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

: The myeloid-to-erythroid ratio supports the evaluation of the bone marrow's cell production and balance. It is not a stand-alone diagnostic test; results are interpreted alongside the complete bone marrow report and other clinical information, and reference ranges vary by laboratory.

Short name

: M:E Ratio

Frequently asked questions

: Is the myeloid-to-erythroid ratio a blood test?
: No. It is calculated from a bone marrow examination, not from a routine blood draw, so it requires a bone marrow sample.
: Does an abnormal ratio always mean there is a disease?
: Not necessarily. The ratio can be affected by many factors, and it must be interpreted with the rest of the bone marrow findings and your clinical information by your care team.
: Will I get a numeric result?
: The ratio is usually reported as a number, but the expected range depends on the laboratory and the person's situation. Your care team will explain what your specific result indicates.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy