Myeloperoxidase Antibody (Serum) - Qualitative

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms or a history suggestive of an autoimmune disease, such as vasculitis (inflammation of blood vessels), or if you’re being evaluated for a suspected immune-related condition. It can also be part of a broader diagnostic workup for unexplained symptoms like skin rashes, joint pain, or organ involvement.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from a vein in your arm. The sample will be sent to a lab for analysis. Results may take several days to a week, depending on lab processes.

What the Test Results Mean

A positive result indicates the presence of myeloperoxidase antibodies, which may suggest an autoimmune response. However, false positives can occur, so results are often interpreted alongside other clinical findings and tests. Your doctor will discuss the meaning of your specific result in the context of your health history and symptoms.

Possible Conditions Linked to Positive Results

Positive myeloperoxidase antibody results are commonly associated with **granulomatosis with polyangiitis (GPA)**, a type of vasculitis that affects blood vessels. Other autoimmune conditions, such as certain forms of lupus or rheumatoid arthritis, may also be linked to these antibodies, though not exclusively.