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Myeloperoxidase Antibody (Serum) - Qualitative

Published: August 9, 2026Updated: August 16, 2026

This test measures whether your blood has antibodies against myeloperoxidase, an enzyme found in white blood cells. It may help diagnose certain autoimmune conditions or blood disorders.

Quick summary

["This test checks for specific antibodies linked to immune system activity in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
46266-3
Short code
Myeloperoxidase Ab Ser IA-aCnc
Synonyms
Myeloperoxidase Ab Ser IA-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ia
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions associated with autoimmune diseases, such as lupus, rheumatoid arthritis, or certain types of vasculitis. It could also be used to monitor or confirm a suspected diagnosis of a blood disorder affecting white blood cells.

What to Expect Before the Test

No special preparation is usually needed. You may have a small needle inserted into your arm to draw blood from a vein. The process is quick and typically painless. If you’re on blood thinners, let your provider know before the test.

What the Test Results Mean

Results are reported as positive or negative. A positive result indicates the presence of antibodies against myeloperoxidase, which may suggest an underlying autoimmune or inflammatory condition. Your provider will discuss these findings in detail with you.

Common Conditions Linked to This Test

This test is often used in the evaluation of conditions like systemic lupus erythematosus (SLE), vasculitis, and certain types of autoimmune hemolytic anemia. It may also be part of a broader diagnostic workup for unexplained symptoms such as fatigue, joint pain, or skin rashes.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Understanding the Role of Myeloperoxidase Antibodies

Short name

Myeloperoxidase Antibody (Serum) - Qual

Frequently asked questions

What does a positive result mean for my health?
A positive result suggests the presence of antibodies targeting myeloperoxidase, which is an enzyme involved in immune responses. This can be indicative of an autoimmune condition, where your immune system mistakenly attacks healthy cells. Your provider will work with you to determine the next steps, which may include further testing or treatment adjustments.
Can this test help diagnose a specific disease?
While this test can support the evaluation of certain autoimmune diseases, it is not definitive on its own. It is often used alongside other tests and clinical findings to narrow down possible diagnoses. Your healthcare provider will interpret the results in the context of your symptoms and medical history.
How often should I get this test?
The frequency of this test depends on your individual health needs and the recommendations of your healthcare provider. If you have an ongoing condition being monitored, they may schedule follow-up tests at regular intervals to track changes in your condition.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy