Myeloperoxidase Antibody Screening by Line Blot
This test detects antibodies related to myeloperoxidase, an enzyme found in white blood cells. It may help identify certain autoimmune conditions or connective tissue disorders.
["This screening helps assess potential autoimmune reactions involving white blood cells."]
Key facts at a glance
- LOINC
- 89507-8
- Short code
- Myeloperoxidase Ab Ser Ql Line blot
- Synonyms
- Myeloperoxidase Ab Ser Ql Line blot
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- line-blot
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Is This Test Measuring?
Myeloperoxidase (MPO) is an enzyme produced by certain white blood cells (neutrophils). Antibodies against MPO can be part of an autoimmune response, where the immune system mistakenly attacks healthy cells. This test checks for the presence of these antibodies in your blood.
Why Might You Need This Test?
Your healthcare provider may order this test if you have symptoms like joint pain, skin rashes, or other signs of autoimmune diseases. It may also be used to monitor conditions like systemic lupus erythematosus (SLE) or other connective tissue disorders.
How Is the Test Performed?
A blood sample is drawn from a vein in your arm. The sample is then tested using a line blot assay, which detects specific antibodies against myeloperoxidase. Results are qualitative (positive or negative) rather than a numeric value.
What Are Possible Results?
A positive result means antibodies against myeloperoxidase were found. A negative result indicates no detectable antibodies. Interpretation depends on clinical context and may require further testing.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results may suggest an autoimmune condition affecting white blood cells or connective tissues. However, false positives can occur, so results should be evaluated alongside other symptoms, medical history, and tests. Consult your doctor for guidance.
Short name
Myeloperoxidase Antibody (Screen)
Frequently asked questions
What does a positive result mean?
Will I need more tests if this result is positive?
How long does it take to get results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy