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Myeloperoxidase Antibody Titration (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of antibodies against myeloperoxidase, an enzyme found in white blood cells. It helps evaluate conditions like autoimmune diseases or certain blood disorders.

Quick summary

["This test may help diagnose or monitor conditions linked to immune system activity or blood cell function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
51801-9
Short code
Myeloperoxidase Ab Titr Ser IF
Synonyms
Myeloperoxidase Ab Titr Ser IF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
if
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions associated with abnormal immune responses, such as chronic inflammation, autoimmune diseases, or certain blood disorders. It could also be used to monitor treatment progress or check for hidden immune-related issues.

What to Expect Before the Test

No special preparation is usually needed. You may fast for 8–12 hours before the test if instructed, but always follow your provider’s specific instructions. Bring any medications you’re taking to discuss with them.

How the Test Is Performed

A blood sample is drawn from a vein in your arm, typically in a clinic or lab setting. The blood is processed to separate serum, which is then tested for myeloperoxidase antibodies using an immunoassay method.

What the Results Mean

Results are qualitative (positive or negative) rather than numeric. A positive result suggests the presence of antibodies against myeloperoxidase, which may indicate an immune response. Your provider will interpret results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated myeloperoxidase antibodies can be linked to autoimmune conditions (e.g., systemic lupus erythematosus) or certain blood disorders (e.g., myeloperoxidase-related vasculitis). They may also appear in people with chronic infections or inflammatory diseases. This test is rarely used alone but can support a broader diagnostic workup.

Short name

Myeloperoxidase Antibody Test

Frequently asked questions

What does a positive result mean?
A positive result means your blood contains antibodies against myeloperoxidase, which may signal an immune response. This could be part of an autoimmune condition, an infection, or another underlying issue. Your doctor will discuss next steps based on your overall health and test results.
Can this test be done at home?
No, this test requires a lab sample collected by a healthcare professional. Blood draws are typically done in a clinic or hospital setting.
How often might I need this test?
Frequency depends on your condition. If ordered for monitoring, your provider may recommend retesting at intervals (e.g., every few months) to track changes in your immune activity or treatment response.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy