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Myeloperoxidase Activity in Peripheral Blood Cells

Published: August 9, 2026Updated: August 16, 2026

This test measures the activity of myeloperoxidase, an enzyme found in white blood cells (neutrophils). It helps assess immune function and inflammation.

Quick summary

["MPO activity can indicate how well your immune system is functioning and whether there may be underlying inflammation or infection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107073-9
Short code
Myeloperoxidase Cells NFr Mar FC
Synonyms
Myeloperoxidase Cells NFr Mar FC
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
86430
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Doctors may order this test to evaluate conditions affecting white blood cells, such as infections, autoimmune diseases, or certain blood disorders. It can also be used in research or specialized diagnostic scenarios where immune cell function is suspected.

What to Expect Before the Test

No special preparation is typically needed. You may donate a small sample of whole blood, often drawn from a vein in your arm. If you’re on blood-thinning medication, let your provider know before the test.

What the Results Mean

Results are not provided with specific numeric ranges in this generic description. Instead, they are interpreted by your healthcare provider based on clinical context, such as symptoms, other test results, and medical history. Elevated or low levels may suggest specific conditions.

Common Conditions Monitored

While not always directly linked to a single disease, abnormal MPO activity can be associated with conditions like chronic inflammation, certain infections, or leukemias. It’s often used in research or specialized settings rather than routine care.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Role in Diagnosis and Research

Short name

Myeloperoxidase (MPO) Activity

Frequently asked questions

How is this test used in clinical practice?
This test is primarily used in specialized research, diagnostic studies, or when evaluating rare conditions involving immune cell dysfunction. It may not be part of standard diagnostic panels for common illnesses like infections or allergies. Your provider will discuss its relevance to your specific situation.
What if my results are outside of typical ranges?
Since reference ranges aren’t provided here, your provider will interpret results in relation to your overall health and medical history. Abnormal findings may prompt further testing or additional evaluation to identify potential causes.
Can I fast before this test?
No fasting is required for this blood test. However, always follow your healthcare provider’s instructions, especially if you’re on medications that might affect blood samples.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy