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Myeloperoxidase Antibody, Serum (Qualitative or Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence or level of antibodies against myeloperoxidase, an enzyme found in white blood cells. It may help diagnose or monitor certain autoimmune conditions.

Quick summary

["This test helps identify immune responses linked to autoimmune diseases or certain blood disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
48404-8
Short code
Myeloperoxidase IgG Ser-aCnc
Synonyms
Myeloperoxidase IgG Ser-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms or conditions associated with an abnormal immune response, such as autoimmune diseases (e.g., lupus, rheumatoid arthritis) or certain blood disorders (e.g., myeloperoxidase-associated vasculitis). It may also be used to monitor treatment effectiveness or rule out specific diagnoses.

What Does the Test Involve?

A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab for analysis. The test may be qualitative (yes/no presence) or quantitative (measuring exact antibody levels), depending on the clinical need.

Sample Collection and Preparation

The blood sample is typically collected in a plain red-topped tube (serum) or a special tube designed for plasma. The sample is then processed to separate serum or plasma for testing. Results may take several days to a week, depending on lab procedures.

What Do Results Mean?

Results may indicate a positive or negative antibody presence. Elevated or abnormal levels could suggest an autoimmune condition or other immune-related disorders. Your provider will interpret results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Myeloperoxidase Antibody Test

Frequently asked questions

What are the possible reasons for this test?
Possible reasons include suspected autoimmune diseases, unexplained blood test abnormalities, or monitoring conditions like vasculitis or rheumatoid arthritis.
How long does it take to get results?
Results can take between a few days to a week, depending on the lab’s processing time and testing method.
Is this test painful?
The blood draw itself may cause mild discomfort or soreness at the injection site, but it is generally well-tolerated. Most people experience minimal pain or no pain during the procedure.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy