Myeloperoxidase Antibody, Serum (Qualitative)
This test checks for the presence of antibodies against myeloperoxidase, an enzyme found in white blood cells. It may help diagnose conditions like autoimmune diseases or certain blood disorders.
["This test can help identify immune system responses linked to blood-related conditions."]
Key facts at a glance
- LOINC
- 97996-3
- Short code
- Myeloperoxidase IgG SerPl IA-aCnc
- Synonyms
- Myeloperoxidase IgG SerPl IA-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Is This Test Done?
Your doctor may order this test if you have symptoms or risk factors for conditions like autoimmune diseases (e.g., lupus), certain blood cancers, or chronic inflammatory disorders. It can also be part of evaluating unexplained blood abnormalities or immune-related symptoms.
What Does the Test Measure?
The test detects IgG antibodies specific to myeloperoxidase, an enzyme produced by white blood cells (neutrophils). Positive results suggest an immune response targeting this enzyme, which may indicate an underlying autoimmune or inflammatory condition.
Sample Collection and Preparation
A blood sample is drawn from a vein in your arm. The serum portion is separated and tested for myeloperoxidase antibodies using a specialized immunoassay method.
What Are Possible Results?
Results are reported as positive or negative. A positive result indicates the presence of myeloperoxidase antibodies, which may warrant further medical evaluation to explore potential causes.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: This test is primarily used to support a diagnosis of autoimmune diseases (e.g., systemic lupus erythematosus) or conditions where the immune system mistakenly attacks its own cells. Elevated antibody levels may also be associated with certain hematologic malignancies or chronic inflammatory disorders. Always discuss results with your healthcare provider, as interpretation depends on your clinical context.
Short name
Myeloperoxidase Antibody (IgG) Test
Frequently asked questions
What does a positive result mean?
How often should I get this test?
Can lifestyle changes affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy