Myeloperoxidase (MPO) in Serum/Plasma
This test measures the level of myeloperoxidase, an enzyme produced by white blood cells called neutrophils. It helps evaluate conditions affecting these cells, such as inflammation or certain blood disorders.
["Myeloperoxidase levels may indicate inflammation or neutrophil activity in your blood."]
Key facts at a glance
- LOINC
- 72515-0
- Short code
- Myeloperoxidase IgG SerPl Ql IF
- Synonyms
- Myeloperoxidase IgG SerPl Ql IF
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- if
- CPT
- 82784
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why Might This Test Be Ordered?
Your healthcare provider may recommend this test if you have symptoms like persistent fever, unexplained infections, or signs of inflammation. It could also be used to monitor conditions like chronic neutropenia, leukemia, or other immune-related disorders.
What Does a Result Mean?
Results are not typically interpreted alone but in the context of your overall health and symptoms. Elevated levels might suggest increased neutrophil activity, while very low levels could indicate a deficiency or immune system dysfunction. Always discuss your results with your doctor.
How Is the Test Performed?
A blood sample is drawn from a vein, usually in your arm. The sample is sent to a lab for analysis. The test measures the enzyme myeloperoxidase in your serum or plasma.
What Are Common Conditions Monitored?
This test is often used to monitor conditions involving abnormal neutrophil activity, such as certain types of leukemia, autoimmune disorders, or infections that affect white blood cells.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Myeloperoxidase plays a key role in the immune response by producing reactive oxygen species to kill bacteria and other pathogens. Abnormal levels may signal underlying inflammatory or hematologic conditions that require further evaluation by your healthcare provider.
Short name
Serum Myeloperoxidase
Frequently asked questions
What does a high myeloperoxidase level mean?
How often should I get this test?
Can diet or lifestyle affect myeloperoxidase levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy