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Myeloperoxidase Antibody (Serum) - Immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against myeloperoxidase, an enzyme found in white blood cells. It may help diagnose conditions like autoimmune diseases or certain blood disorders.

Quick summary

["This test can support diagnosis of conditions linked to immune system activity or blood cell abnormalities."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
81771-8
Short code
Myeloperoxidase IgG Ser Ql IB
Synonyms
Myeloperoxidase IgG Ser Ql IB
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
ib
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms or a medical history suggestive of conditions like autoimmune diseases (e.g., lupus, rheumatoid arthritis), certain blood cancers, or other immune-related disorders. It may also be used in research or specialized diagnostic settings.

What to Expect Before the Test

No special preparation is usually needed. You’ll provide a blood sample, typically drawn from a vein in your arm. If you’re on blood-thinning medication, let your doctor know before the test.

What the Test Results Mean

Results may indicate abnormal immune activity or the presence of specific antibodies. Elevated levels could suggest autoimmune conditions or other immune-related issues, but results alone don’t diagnose a condition. Your doctor will interpret results in the context of your symptoms and medical history.

Common Conditions Linked to This Test

This test is often used to help identify conditions where antibodies against myeloperoxidase play a role, such as certain types of vasculitis (inflammation of blood vessels) or autoimmune hemolytic anemia (a condition where your body attacks its own red blood cells).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Myeloperoxidase Antibody (IgG)

Frequently asked questions

What does a positive or elevated result mean?
A positive or elevated result may suggest an immune response targeting myeloperoxidase, which could be linked to autoimmune diseases or other conditions affecting the immune system. However, many people test positive without symptoms, so results should always be reviewed by your healthcare provider.
Can this test be used to diagnose a specific disease?
No, this test alone cannot diagnose a specific disease. It may be used as part of a broader evaluation, including clinical symptoms, other test results, and medical history, to help identify potential conditions like autoimmune disorders or vasculitis.
How often should I get this test?
The frequency depends on your symptoms, medical history, and ongoing treatment. Your doctor will determine how often this test is needed based on your individual care plan.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy