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Myoglobin, 24-Hour Urinary Excretion

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of myoglobin, a protein found in muscle cells, that your body releases into your urine over a 24-hour period. It helps assess muscle damage or conditions that may cause myoglobin release.

Quick summary

["This test helps identify muscle injuries or diseases that release myoglobin into urine."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
68960-4
Short code
Myoglobin 24h Ur Ql
Synonyms
Myoglobin 24h Ur Ql
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
0
Ref high
70
Critical range
— – 200 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83880
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like muscle pain, weakness, or dark-colored urine, which could indicate muscle damage. It may also be used to monitor conditions like rhabdomyolysis (severe muscle breakdown) or certain muscle diseases.

What Does the Test Involve?

You’ll collect all your urine over a 24-hour period in a special container. The urine is then sent to a lab for analysis to measure myoglobin levels.

What Are Possible Results?

Results are typically reported as the total amount of myoglobin excreted in the urine over 24 hours. Elevated levels may suggest muscle damage or other underlying conditions.

What Does Elevated Myoglobin Mean?

High urinary myoglobin levels can signal muscle injury, such as from overexertion, trauma, or certain medical conditions. It may also indicate kidney problems if myoglobin builds up in the bloodstream and affects kidney function.

Reference range

Adult males: 20-70 μg/L; Females: 25-58 μg/LN/A

Specimen: urine

No special preparation required. Inform provider of any chest pain or symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated myoglobin in urine can be a marker for muscle breakdown, which may require medical attention to prevent complications like kidney damage. Always discuss results with your healthcare provider for personalized guidance.

Short name

Urinary Myoglobin Over 24 Hours

Frequently asked questions

What causes elevated myoglobin levels in urine?
Elevated myoglobin can result from muscle injuries (e.g., strains, crush injuries), severe muscle diseases, or conditions like rhabdomyolysis. Certain medications or infections may also play a role.
How soon will I get my results?
Results are typically available within 1–3 business days, depending on lab processing times. Your healthcare provider will contact you with the final report.
Can I eat or drink normally before this test?
Yes, you can eat and drink as usual, but avoid excessive exercise or muscle-strenuous activities for 24 hours before testing to prevent false elevations.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy